Most Replayed Moment: Mouthwash REVERSES The Benefits Of Exercise! Dr Nathan Bryan

The Diary Of A CEO with Steven Bartlett24mApril 3, 2026

Get the full intelligence

Search transcripts, export clips, track mentions, and explore all topics from “Most Replayed Moment: Mouthwash REVERSES The Benefits Of Exercise! Dr Nathan Bryan” inside PodZeus.

AI-Generated Summary

In this most replayed episode of The Diary Of A CEO, Dr. Nathan Bryan reveals a startling connection between everyday oral hygiene habits and systemic health. He explains that fluoride in toothpaste and antiseptic mouthwash destroy the oral microbiome, which is essential for producing nitric oxide—a molecule critical for cardiovascular health, exercise benefits, hormone regulation, and wound healing. Using data from clinical studies and historical context, Bryan argues that routine mouthwash use nullifies the cardioprotective effects of exercise, while sugar, antacids, and mouth breathing further impair nitric oxide production. He advocates for a holistic approach: eliminating fluoride and sugar, avoiding antacids, practicing nasal breathing and tongue scraping, and embracing sunlight and red light therapy to naturally boost nitric oxide. The episode underscores how small daily choices—like brushing with non-fluoridated toothpaste or stopping mouthwash—can have profound, life-altering health impacts.

Key Takeaways
1

Using antiseptic mouthwash cancels out the cardiovascular benefits of exercise by destroying nitric oxide-producing oral bacteria.

2

Fluoride in toothpaste is a neurotoxin linked to lowered IQ in children and thyroid dysfunction; non-fluoridated alternatives are essential.

3

Sugar and high-glycemic foods impair nitric oxide production by binding to and disabling the enzymes responsible for its synthesis.

4

Nasal breathing and humming activate nitric oxide production in the sinuses, improving oxygenation and lowering blood pressure.

5

Sunlight, red light therapy, and infrared exposure stimulate nitric oxide release and support mitochondrial health and longevity.

Chapters
0:00
5 min

The Hidden Dangers of Fluoride and Mouthwash

Fluoride, there's no benefit of fluoride and it's all risk. It lowers IQ in kids by as much as seven points.

Highlight
5:00
5 min

How Mouthwash Kills the Benefits of Exercise

If you do that and you're using mouthwash, you no longer get the benefits from exercise.

Highlight
10:00
5 min

Sugar, Antacids, and the Nitric Oxide Crisis

Bryan explains how sugar and antacids like PPIs destroy nitric oxide production by damaging enzymes and impairing nutrient absorption. He warns that 75% of Americans are magnesium-deficient and 95% are iodine-deficient due to suppressed stomach acid.

15:00
5 min

The Power of Nasal Breathing and Humming

Nasal breathing and humming activate nitric oxide synthase in the sinuses, improving oxygen delivery and lowering blood pressure. Mouth breathing disrupts this process and alters the oral microbiome, reducing nitric oxide levels.

20:00
5 min

Light Therapy and Lifestyle for Nitric Oxide Boost

Sunlight, red light therapy, and infrared exposure stimulate nitric oxide release by breaking bonds with proteins and metals. Dr. Bryan advocates daily exposure to natural and artificial light for improved energy, circulation, and longevity.

High-Impact Quotes
Fluoride, there's no benefit of fluoride and it's all risk. It lowers IQ in kids by as much as seven points.
Dr. Nathan Bryan1:14
Viral: 90.0
If you do that and you're using mouthwash, you no longer get the benefits from exercise.
Dr. Nathan Bryan5:31
Viral: 85.0
Sugar is an absolute poison, and it kills many enzymes and binds to everything.
Dr. Nathan Bryan9:46
Viral: 80.0
Speakers

Host

Steven Bartlett

Guest

Dr. Nathan Bryan
Topics Discussed
nitric oxide production98%oral microbiome health95%antiseptic mouthwash risks92%fluoride toxicity90%sugar and insulin resistance88%antacid and PPI dangers87%nasal breathing benefits85%light therapy for health80%
People & Brands

Dr. Nathan Bryan

person

15xPositive

nitric oxide

other

14xPositive

Steven Bartlett

person

12xNeutral

fluoride

other

10xNegative

antiseptic mouthwash

product

8xNegative

sugar

other

7xNegative

beetroot

other

6xNeutral

National Toxicology Program

organization

2xNegative

Prilosec

product

2xNegative

Nexium

product

2xNegative

Get the full intelligence

Search transcripts, export clips, track mentions, and explore all topics from “Most Replayed Moment: Mouthwash REVERSES The Benefits Of Exercise! Dr Nathan Bryan” inside PodZeus.

Start discovering podcast insights today

Start with a 7-day trial and explore a growing catalog of popular podcasts. No credit card required.

No credit card required • 7-day trial • Cancel anytime