The Last Alchemist, Part Two

The Constant: A History of Getting Things Wrong1h 7mApril 7, 2026

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AI-Generated Summary

In the second part of 'The Last Alchemist,' host Mark Kreisler traces the transmission of alchemy from ancient Alexandria through the Arab world to medieval Europe, highlighting the pivotal role of Robert of Chester’s 1144 Latin translation of an Arabic alchemical text. This translation ignited a European alchemical tradition steeped in secrecy, pseudonyms, and the pursuit of the Philosopher’s Stone. Kreisler explores how European alchemists, despite being influenced by Aristotle’s empiricism, became entangled in a labyrinth of coded texts, frauds, and failed experiments. He examines the rise of legendary figures like Albertus Magnus and Roger Bacon, whose real scientific contributions were overshadowed by myths of magical inventions and demonic pacts. The episode dissects the infamous case of Marco Bragadino, a con artist who duped Venice and the Duke of Bavaria before being executed. Kreisler then turns to James Price, the 'Last Alchemist,' whose 1782 demonstrations of gold and silver production caused a sensation—only to collapse when he failed to reproduce results before the Royal Society. Price’s mysterious death from prussic acid (hydrogen cyanide) during a final demonstration marks a poetic end to alchemy’s long quest. The episode concludes with the realization that alchemy, though discredited, laid the foundation for modern chemistry, with figures like Paracelsus, Boyle, and Newton contributing significantly despite their alchemical pursuits. The episode underscores that alchemy was not merely superstition but a rigorous, experimental precursor to chemistry. Its downfall stemmed not from inherent nonsense, but from its entanglement with fraud, secrecy, and state fears of economic destabilization. The legal bans on alchemical gold production, from Pope John XXII’s 1317 decretal to England’s 1404 Law Against Multipliers, reflect deep-seated anxieties about unregulated wealth. Yet, the real legacy lies in the scientific methods and discoveries—alcohol, arsenic, sulfuric acid, porcelain—that emerged from alchemical practice. Kreisler argues that alchemy’s end was not a failure of science, but a necessary split: chemists shed alchemy’s mysticism to become a legitimate discipline. The story of James Price, who may have knowingly or unknowingly poisoned himself while attempting to replicate a real chemical breakthrough, symbolizes this transition—where the last alchemist died not in failure, but in the moment of scientific revelation, just before the truth was fully understood.

Key Takeaways
1

Alchemy was not mere superstition but a rigorous, experimental precursor to modern chemistry, producing real scientific advances like alcohol, arsenic, and sulfuric acid.

2

The transmission of alchemy to Europe via Robert of Chester’s 1144 Latin translation sparked a tradition of secrecy, pseudonyms, and coded texts that made it nearly impossible to verify or falsify claims.

3

The real danger in alchemy wasn’t the pursuit of gold, but the fraud and deception that plagued it—exemplified by con artists like Marco Bragadino, who exploited noble desperation and public gullibility.

4

James Price’s failed demonstration in 1783 marked the symbolic end of alchemy: he may have been a fraud, a deluded believer, or a tragic figure who unknowingly poisoned himself while attempting a real chemical experiment.

5

The split between alchemy and chemistry was not a rejection of science, but a necessary purification—chemists shed mysticism and secrecy to become a legitimate, open, and reproducible science.

…and 2 more takeaways available in PodZeus

Chapters
0:00
10 min

The Dark Forest of Alchemy’s Origins

The episode opens with a recap of alchemy’s murky beginnings in Alexandria and its uncertain transmission to the Arab world. Kreisler emphasizes the lack of reliable records, pseudonyms, and coded writings that make early alchemy nearly impossible to verify, setting the stage for the mystery that defines the entire tradition.

10:00
10 min

Robert of Chester and the Birth of European Alchemy

Robert of Chester’s 1144 Latin translation of an Arabic alchemical text marks the true beginning of European alchemy. Kreisler explores the mystery surrounding Robert’s identity and the cultural shock Europeans felt upon discovering that their Christian rivals had preserved and advanced knowledge they had lost.

20:00
20 min

The Alchemical Crossword Puzzle and the Rise of Fraud

The problem with alchemy wasn't just the fraud. It was that alchemy could never disentangle itself from the fraud, nor from the less rational, more occult and magical aspects it ran around with.

Highlight
40:00
20 min

The Myth and Reality of Albertus Magnus and Roger Bacon

Kreisler separates legend from fact in the lives of Albertus Magnus and Roger Bacon, two towering figures of medieval science. While both were real polymaths and empiricists, their reputations were inflated by myths of demonic pacts, time-traveling inventions, and the Brazen Head.

1:00:00
20 min

The Final Alchemist: James Price and the End of an Era

In a poetic sense, at least, alchemy ended there, in Guildford, on August 3rd, 1783, with one last perverse bit of misbegotten transmutation, when the golden boy of the Royal Academy became a dark and leaded cautionary tale.

Highlight
High-Impact Quotes
In a poetic sense, at least, alchemy ended there, in Guildford, on August 3rd, 1783, with one last perverse bit of misbegotten transmutation, when the golden boy of the Royal Academy became a dark and leaded cautionary tale.
Mark Kreisler64:34
Viral: 90.0
Alchemy gave us alcohol and arsenic and zinc and antimony carbon steel and porcelain sulfuric acid hydrochloric acid phosphorus Multiple dyes and paints, medicines and tools. Basically any and every instrument used in chemistry if it existed before the 18th century was invented by an alchemist because alchemy was chemistry.
Mark Kreisler52:34
Viral: 88.0
The problem with alchemy wasn't just the fraud. It was that alchemy could never disentangle itself from the fraud, nor from the less rational, more occult and magical aspects it ran around with.
Mark Kreisler37:45
Viral: 85.0
Speakers

Host

Mark Kreisler
Topics Discussed
History of Alchemy95%Scientific Legacy of Alchemy94%Alchemy to Chemistry92%Transmission of Knowledge90%Fraud and Deception in Science88%Philosopher's Stone87%Medieval Science and Philosophy85%Empiricism and Experimentation83%
People & Brands

The Philosopher's Stone

other

15xNeutral

Mark Kreisler

person

15xNeutral

James Price

person

12xMixed

Marco Bragadino

person

10xNegative

Robert of Chester

person

8xPositive

The Royal Society

organization

8xNeutral

Roger Bacon

person

7xPositive

Albertus Magnus

person

6xPositive

Nicholas Flamel

person

5xNeutral

Marianos

person

5xNeutral

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