I Stop AG1 Six Months Ago. Here's What Happened...(#362 Mindfulness, Resilience, Growth Mindset)

Whole Again: A Fresh Approach to Mindfulness and Resilience Through Kintsugi Wisdom17mApril 22, 2026

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AI-Generated Summary

Michael Schiff, host of *Whole Again*, reveals he stopped taking AG1—a popular green powder supplement—six months ago after a deep personal reckoning during his recovery from a severe femur fracture. Rather than relying on marketing hype, he conducted a rigorous self-experiment: he paused all supplements, including AG1, and monitored his health through comprehensive blood work. The results? No changes in any biomarkers—neither positive nor negative—leading him to conclude the supplement was likely a placebo. He argues that most supplement claims lack long-term, clinically meaningful evidence, often relying on short-term, statistically significant but practically irrelevant data. He criticizes the lack of transparency in clinical trials, the absence of conflict-of-interest disclosures, and the high cost of supplements that may do little more than make your urine expensive. His core message: before spending hundreds on supplements, test your own body’s response and prioritize real, whole foods over marketed 'magic' powders. This episode is a call for discernment in a world saturated with wellness noise.

Key Takeaways
1

Stop taking supplements like AG1 without testing their real impact on your body through blood work.

2

Statistical significance in studies doesn't equal clinical significance—what matters is how you feel and perform in real life.

3

Most supplement trials are short-term, small-scale, and often lack transparency about funding or participant details.

4

AG1 did not change any of Michael’s blood markers after six months of discontinuation—suggesting it had no measurable physiological effect.

5

Fat-soluble supplements like vitamins A, D, E, and K can accumulate and harm organs if taken in excess without medical oversight.

…and 3 more takeaways available in PodZeus

Chapters
0:00
2 min

The Supplement Paradox: More Isn’t Always Better

Michael introduces the episode by questioning the overwhelming pressure to take multiple supplements, setting the stage for a critical examination of their real-world effectiveness and the flaws in how they're marketed.

2:00
3 min

The Myth of Clinical Significance: Why Studies Lie

Michael breaks down the difference between statistical significance and clinical significance, exposing how short-term, small-scale trials with no long-term follow-up are used to sell supplements without proving real-world benefits.

5:00
5 min

The AG1 Experiment: A Six-Month Self-Test

After stopping AG1 for about four months, now going on month six, is that none of my blood lab levels changed at all. Nothing got worse. Remarkable, right?

Highlight
10:00
4 min

The Hidden Costs of Supplements: Money, Placebo, and Risk

Michael warns about the financial cost of supplements, the risk of nutrient buildup (especially fat-soluble vitamins), and the danger of taking multiple supplements without medical coordination.

14:00
4 min

The Real Solution: Whole Foods Over Marketing Hype

Michael concludes that real food—especially a 97% plant-based diet rich in fiber and gut-friendly diversity—provides nutrients more effectively and safely than any supplement powder.

High-Impact Quotes
After stopping AG1 for about four months, now going on month six, is that none of my blood lab levels changed at all. Nothing got worse. Remarkable, right?
Michael Schiff13:49
Viral: 88.0
The product is super expensive. It's like a dollar and a half for each serving. And what they didn't share in the pitch for you to buy it is that you need to take three servings within 24 hours of a big workout.
Michael Schiff7:03
Viral: 70.0
I stopped it. And I feel great. I still have great energy. I feel healthy. And I've also made a commitment to continue to double down on eating as best as I can real food.
Michael Schiff14:17
Viral: 65.0

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