Do THIS Every Day to Rewire Your Brain From Stress and Anxiety

The Mel Robbins Podcast1h 14mApril 27, 2026

Get the full intelligence

Search transcripts, export clips, track mentions, and explore all topics from “Do THIS Every Day to Rewire Your Brain From Stress and Anxiety” inside PodZeus.

AI-Generated Summary

In this powerful episode of The Mel Robbins Podcast, host Mel Robbins welcomes Dr. Nadine Burke Harris, a pioneering pediatrician and former Surgeon General of California, to explore how adverse childhood experiences (ACEs) shape adult behavior, emotions, and health through biological and neurological mechanisms. Dr. Burke Harris explains that trauma is not the event itself, but the body's lasting response to overwhelming stress, which can become a chronic, overactive stress response that persists into adulthood. She reveals how childhood adversity—such as abuse, neglect, or household dysfunction—can alter brain development, immune function, and even gene expression through epigenetics, leading to long-term health issues like heart disease, autoimmune disorders, and mental health challenges. The episode emphasizes that healing is possible through 'buffering'—intentional practices that regulate the nervous system, including mindfulness, exercise, therapy (like EMDR), and supportive relationships. Robbins shares her own journey of recognizing childhood trauma and using daily self-regulation practices to reclaim control over her emotions and relationships. The episode concludes with a hopeful call to action: by creating personal systems of care and connection, individuals can rewire their biology, heal from the past, and build a more resilient, compassionate life.

Key Takeaways
1

Trauma is the body's biological response to stress, not the event itself, and can become a lifelong overactive stress response.

2

Adverse Childhood Experiences (ACEs) are strongly linked to adult health problems like heart disease, autoimmune disorders, and mental health challenges—even without unhealthy behaviors.

3

Buffering—safe, stable relationships and self-regulation practices like mindfulness, exercise, and therapy—can rewire the nervous system and reduce the impact of past trauma.

4

Epigenetics shows that nurturing care can change how genes are expressed, meaning healing is possible even after early adversity.

5

Corrective experiences (like being present for your younger self) help rewire the brain and nervous system, creating new, healthier patterns.

…and 3 more takeaways available in PodZeus

Chapters
0:00
10 min

The Hidden Roots of Adult Reactivity

Our medical expert today is a world-renowned expert on the long-term impact of childhood trauma and adverse experiences. And before you go, okay, no, no, no, I haven't had trauma. I want you to listen to this. Because it is going to explain so much about who you are and who some of the people that you love deeply are right now in your adult life.

Highlight
10:00
10 min

What Is Trauma? The Body’s Response, Not the Event

Trauma is the biological response to overwhelming stress. So a lot of us think of it as the stressor, the thing that happened to us, but it's actually the body's reaction to that stress.

Highlight
20:00
20 min

The ACE Study: How Childhood Adversity Shapes Adult Health

The good news is that if you've experienced these ACEs and you don't engage in any health-damaging behavior, you're not sedentary, you eat really healthy, you exercise regularly, that removes about 50% of the risk. But the other half of the risk... was just the adverse childhood experience?

Highlight
40:00
20 min

The Teeter-Totter Model: Balancing Stress and Buffering

The younger you are when you experience a stressor or trauma or adversity, you need way more buffering on the other side to be able to balance that out.

Highlight
1:00:00
20 min

Epigenetics and the Power of Corrective Experiences

Even if you have had a lot of adverse experiences... the research shows that if you recognize that and you provide that to yourself now, that changes you. And it changes your DNA almost in terms of what's firing.

Highlight
High-Impact Quotes
Trauma is the biological response to overwhelming stress. So a lot of us think of it as the stressor, the thing that happened to us, but it's actually the body's reaction to that stress.
Dr. Nadine Burke Harris7:23
Viral: 92.0
Even if you have had a lot of adverse experiences... the research shows that if you recognize that and you provide that to yourself now, that changes you. And it changes your DNA almost in terms of what's firing.
Dr. Nadine Burke Harris34:58
Viral: 90.0
Infrastructures are love in action. What we build, the systems that we build in our personal lives for ourselves, whether it is connecting to a strong group of friends who we feel safe with. Right? But building it ahead of time and not waiting for the wheels to fall off the cart.
Dr. Nadine Burke Harris70:26
Viral: 89.0
Speakers

Host

Mel Robbins

Guest

Dr. Nadine Burke Harris
Topics Discussed
adverse childhood experiences95%trauma and the nervous system93%buffering and self-regulation90%epigenetics and healing88%corrective experiences87%ACEs and long-term health86%emotional reactivity in adults85%EMDR and trauma therapy80%
People & Brands

Dr. Nadine Burke Harris

person

25xNeutral

Mel Robbins

person

12xPositive

ACEs

other

11xPositive

Adverse Childhood Experiences Study

other

6xPositive

epigenetics

other

5xPositive

EMDR

other

4xPositive

trauma-informed care

other

3xPositive

teeter-totter model

other

3xPositive

The Deepest Well

book

2xPositive

Center for Youth Wellness

organization

2xPositive

Get the full intelligence

Search transcripts, export clips, track mentions, and explore all topics from “Do THIS Every Day to Rewire Your Brain From Stress and Anxiety” inside PodZeus.

Start discovering podcast insights today

Start with a 7-day trial and explore a growing catalog of popular podcasts. No credit card required.

No credit card required • 7-day trial • Cancel anytime