Building a domestic nuclear fuel supply chain

Catalyst with Shayle Kann38mApril 2, 2026

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AI-Generated Summary

In this episode of Catalyst, host Shayle Kann explores the critical but often overlooked nuclear fuel supply chain in the U.S., focusing on the strategic vulnerabilities tied to enrichment. With 25% of U.S. enrichment currently sourced from Russia—despite a 2024 congressional ban that expires in 2028—the nation faces a looming energy security crisis. Scott Nolan, CEO of General Matter, joins to explain how the U.S. has lost its domestic enrichment capacity since the 1990s due to outdated technology and global competition, leaving the country reliant on foreign suppliers. Nolan’s company is building a new enrichment facility in Paducah, Kentucky, leveraging a historic DOE award to produce both low-enriched uranium (LEU) and high-assay low-enriched uranium (HALU) for next-generation reactors. The episode underscores the 'chicken or egg' dilemma in advancing nuclear innovation: advanced reactors need fuel, but fuel producers won’t invest without demand. Nolan argues that government support is essential to break the deadlock. The discussion also highlights broader supply chain gaps, including limited U.S. conversion and mining capacity, with calls for regulatory reform to enable domestic uranium production. Key takeaways include: 1) The U.S. must rebuild its domestic enrichment capacity to avoid energy dependency on adversarial nations; 2) HALU production is essential for advanced reactors and currently only available from Russia; 3) Government incentives like the DOE award are crucial to de-risking private investment in strategic infrastructure; 4) Streamlining uranium mining permits could unlock domestic supply chain resilience; 5) The nuclear fuel supply chain is not just a technical challenge but a geopolitical and regulatory one. The overall tone is cautiously optimistic, emphasizing that with targeted investment and policy reform, the U.S. can achieve energy security in nuclear fuel.

Key Takeaways
1

The U.S. must rebuild domestic enrichment capacity to avoid reliance on adversarial nations like Russia.

2

HALU (high-assay low-enriched uranium) is essential for next-gen reactors and currently only available from Russia.

3

Government incentives are critical to breaking the 'chicken or egg' cycle in advanced nuclear deployment.

4

Streamlining uranium mining permits could unlock domestic supply chain resilience.

5

The nuclear fuel supply chain is as much a regulatory and geopolitical challenge as it is a technical one.

Chapters
0:00
5 min

The Hidden Vulnerability in the Nuclear Supply Chain

The last thing we want, obviously, is to scale up an industry that introduces a new supply chain dependency that we're going to regret later. So clearly better to fix it now.

Highlight
5:00
10 min

The Five-Step Nuclear Fuel Supply Chain

Scott Nolan walks through the full nuclear fuel cycle: mining, conversion, enrichment, deconversion, and fuel fabrication. He emphasizes that while the U.S. handles all steps except enrichment at commercial scale, the bottleneck lies in enrichment, with no domestic commercial-scale facilities operating today.

15:00
15 min

The Geopolitical Risks of Russian Enrichment Dependence

We went from a place of 86% global market share down to less than 0.1% today by U.S. companies or U.S. entities.

Highlight
30:00
15 min

General Matter’s Mission: Building Domestic HALU Capacity

If we rewind to like late 2022 at Founders Fund, I was looking at all the advanced reactors companies deciding to invest in one. I asked them what the hardest thing about building their company was going to be and it was purchasing fuel.

Highlight
45:00
21 min

The Future of the U.S. Nuclear Supply Chain and Policy Reform

The conversation turns to long-term vision: a fully domestic supply chain from mining to fuel fabrication. Nolan calls for regulatory reform to streamline uranium mining permits, especially for ISR (in-situ recovery) methods, which are less environmentally impactful. He emphasizes that energy security requires systemic change across the entire supply chain.

High-Impact Quotes
We went from a place of 86% global market share down to less than 0.1% today by U.S. companies or U.S. entities.
Scott Nolan27:00
Viral: 90.0
If we rewind to like late 2022 at Founders Fund, I was looking at all the advanced reactors companies deciding to invest in one. I asked them what the hardest thing about building their company was going to be and it was purchasing fuel.
Scott Nolan22:42
Viral: 88.0
The last thing we want, obviously, is to scale up an industry that introduces a new supply chain dependency that we're going to regret later. So clearly better to fix it now.
Shayle Kann0:56
Viral: 85.0
Speakers

Host

Shayle Kann

Guest

Scott Nolan
Topics Discussed
Nuclear Fuel Supply Chain95%U.S. Energy Security90%Enrichment Technology88%Advanced Reactors and HALU85%Geopolitical Risks in Energy82%U.S. Uranium Mining and Permitting78%Government Incentives and DOE Support75%Tolling Model in Nuclear Fuel70%
People & Brands

Scott Nolan

person

45xPositive

General Matter

organization

38xPositive

Russia

place

18xNegative

LEU

other

15xNeutral

DOE

organization

15xPositive

Paducah Gaseous Diffusion Plant

other

12xNeutral

HALU

other

12xPositive

U-308

other

10xNeutral

UF6

other

8xNeutral

Honeywell

organization

7xNeutral

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