Episode 58: ASM Roundup - Day 1 with Dr Marinka Twilt
Get the full intelligence
Search transcripts, export clips, track mentions, and explore all topics from “Episode 58: ASM Roundup - Day 1 with Dr Marinka Twilt” inside PodZeus.
At the 2026 Canadian Rheumatology Association Annual Scientific Meeting in Halifax, Dr. Daniel Ennis and Dr. Janet Pope deliver a live, on-site roundup with Dr. Marinka Twilt, Program Committee Chair, capturing Day 1’s most impactful moments. The episode reveals a stark gap in pediatric rheumatology research: while adult trials are abundant, pediatric studies remain limited to case series and cohort data, with no industry-sponsored clinical trials. Dr. Twilt highlights the growing recognition of autoinflammatory diseases like PFAPA and SERV—conditions that often persist into adulthood—underscoring the need for better pediatric-adult collaboration. A standout moment comes from the two-year follow-up of the SELECT GCA trial, showing upadacitinib maintained 70% remission at year two, challenging the assumption that treatment can be safely stopped after one year. The keynote by Dr. Elizabeth Volkman delivers a paradigm-shifting message: childhood trauma is a significant, underrecognized risk factor for autoimmune disease onset and chronic pain syndromes in adulthood. She advocates for integrating trauma-informed care into rheumatology, urging clinicians to ask about life history and validate patient experiences—something that can be done with low-cost, accessible tools like breathing exercises and yoga.
Pediatric rheumatology lacks industry-sponsored clinical trials—most research remains case series or cohort studies, limiting evidence-based treatment options.
Upadacitinib maintained 70% remission in GCA patients at two years, suggesting long-term treatment may be necessary to prevent flares after initial induction.
Childhood trauma is a significant, underrecognized risk factor for autoimmune disease and chronic pain syndromes in adulthood—clinicians should routinely screen for it.
Trauma-informed care improves patient outcomes: simple, low-cost interventions like breathing exercises, yoga, and walking can significantly enhance well-being and treatment adherence.
Rare diseases are often missed because clinicians rely too heavily on standard tests—biopsy, clinical history, and interdisciplinary dialogue are essential diagnostic tools.
…and 3 more takeaways available in PodZeus
Welcome to ASM 2026 in Halifax
Hosts Dr. Daniel Ennis and Dr. Janet Pope introduce the live special episode from the Canadian Rheumatology Association’s 2026 Annual Scientific Meeting in Halifax, Nova Scotia, with sponsorship from Celtrion Healthcare and editorial oversight by an independent CRA committee.
Year in Review: Pediatric Gaps and Autoinflammation
“There's no clinical trials. If we're lucky, they're cohort studies. Most of the time, they're case series.”
SELECT GCA Trial: Two-Year Follow-Up
“The UPA continuation group had a 70% remission rate versus around 30% in the placebo group.”
Tough-to-Treat: A Misunderstood Term
“We apparently still use this term also not very clearly with what we, like I would have expected or what maybe other people had expected.”
Clinical Pearls & Medical Mysteries: The Art of Diagnosis
“You have to read the words. You have to talk to your other colleagues that are helping to co-manage or helping you.”
“Many people that she sees with chronic autoimmune, especially she has a large scleroderma population, have had really bad childhood trauma, death of a loved one, separations of parents, abuse, et cetera.”
“The UPA continuation group had a 70% remission rate versus around 30% in the placebo group.”
“What can you do for you? That's where you can work as a team or they can feel more empowered, as she was saying, in their own care.”
Hosts
Guest
Dr. Marinka Twilt
person
Dr. Janet Pope
person
Dr. Daniel Ennis
person
Dr. Elizabeth Volkman
person
Canadian Rheumatology Association
organization
Dr. Elizabeth Stringer
person
Dr. Alex Legger
person
Celtrion Healthcare
organization
Dr. Prutin-Raman
person
Dr. Lisa Christopher Stein
person
Episode 59: ASM Roundup - Day 2 with Dr. Marinka Twilt and Dr. Mo Osman
Around the Rheum with Drs. Daniel Ennis & Janet Pope • 26m • 4/18/2026
Episode 60: ASM Roundup - Day 3 with Dr. Marinka Twilt and Dr. Mo Osman
Around the Rheum with Drs. Daniel Ennis & Janet Pope • 19m • 4/19/2026
Episode 61: A Living Legend - Dr. Proton Rahman, Member of the Order of Canada
Around the Rheum with Drs. Daniel Ennis & Janet Pope • 39m • 5/22/2026
Get the full intelligence
Search transcripts, export clips, track mentions, and explore all topics from “Episode 58: ASM Roundup - Day 1 with Dr Marinka Twilt” inside PodZeus.
Start discovering podcast insights today
Start with a 7-day trial and explore a growing catalog of popular podcasts. No credit card required.
No credit card required • 7-day trial • Cancel anytime
